A Phenomenological Study of Computer Science Lecturers: Lived Experiences of Curriculum Design

This hermeneutic phenomenological study presents a description of computer science lecturers’ experiences of curriculum design of degree programmes during a time of transition in curriculum design policy, specifically in the context of Technological University Dublin (DIT). It examines the lived experiences of computer science lecturers to highlight the issues and problems relating to lecturers’ lived experiences of curriculum design, and it describes how it is to be a computer science lecturer in a time of policy change for curriculum design. The findings are that lecturers have been, and are, struggling to cope with the transition from year-long to semesterised courses, that they feel pressured and overworked, but continue to try to adapt from feelings of professionalism and concern to provide curricula that suit the courses. They feel resentful about the lack of preparation and information that might have been given to them prior to, and during, the change. The literature has suggested that further investigation into the effects of institutional policy change on lecturers ought to be carried out. There have been recommendations for the design of degree programmes in Irish institutes, including DIT and its School of Computing. These recommendations form the basis for the quality assurance of the educational programmes to which they are applied. It follows that any divergence between recommended best practice and the experiences of those designing the curricula has serious implications for the assurance on offer. This study has two parts, conducted using hermeneutic phenomenological assumptions and methodology to collect, analyse and interpret data from semi-structured interview transcripts. The preliminary study involved twelve computer science lecturers. The findings of this work served the context to a more in-depth study of the same participants’ experiences. This second study led to findings that describe the computer science lecturers’ lived experiences as curriculum designers. Findings relate to conditions and issues of curriculum design, and lead to the identification of implications for groups and individuals associated with third-level education. This research encourages readers to thoughtfully reflect on what is it like for these computer science lecturers as curriculum designers, and become better informed about what happens during the process of curriculum and module design. The full significance of such reflection will ideally promote further questioning and inquiry, in keeping with the provisional nature of phenomenological inquiry

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Phenomenology and Hermeneutic Phenomenology: the Philosophy, the Methodologies and Using Hermeneutic Phenomenology to Investigage Lecturers\u27 Experiences of Curriculum Design

This article investigates the philosophy of phenomenology, continuing to examine and describe it as a methodology. There are different methods of phenomenology, divided by their different perspectives of what phenomenology is: largely grouped into the two types of descriptive and interpretive phenomenology. The focal methodology is hermeneutic phenomenology – one type of phenomenological methodology among interpretive phenomenological methodologies. The context for phenomenology and the location of hermeneutic phenomenology is explained through its historic antecedents. When using phenomenology as a methodology there are criteria for data gathering and data analysis and examples of these are cited in this paper. Also in this paper we give examples from a study of curriculum design of thematic statements, defining whether they are useful data for a hermeneutic phenomenological study

Ventricular Pacing in Children

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75351/1/j.1540-8159.1982.tb06565.x.pd

Comparison of p53 and DNA content abnormalities in adenocarcinoma of the oesophagus and gastric cardia.

This study examined the association between 17p allelic loss, p53 gene mutation, p53 protein expression and DNA aneuploidy in a series of adenocarcinomas arising in the oesophagus and gastric cardia. 17p allelic loss was detected in 79% (15 of 19) of oesophageal and in 83% (29 of 35) of gastric adenocarcinomas. p53 mutations were detected in 70% (14 of 20) and 63% (26 of 41) of oesophageal and of gastric adenocarcinomas respectively. Both tumour types were associated with a predominance of base transitions at CpG dinucleotides. In five cases of oesophageal adenocarcinoma, the same mutation was detected both in tumour and in adjacent dysplastic Barrett's epithelium. Diffuse p53 protein expression was detected in 65% (13 of 20) and 59% (24 of 41) of oesophageal and of gastric tumours, respectively, and was associated with the presence of p53 missense mutation (Chi-squared, P < 0.0001). DNA aneuploidy was detected in 80% (16 of 20) of oesophageal and in 70% (28 of 40) of gastric tumours. No association was found between p53 or DNA content abnormalities and tumour stage or histological subtype. In conclusion, this study detected a similar pattern of p53 alterations in adenocarcinoma of the oesophagus and gastric cardia--molecular data consistent with the observation that these tumours demonstrate similar clinical and epidemiological features

Clinic Blood Pressure Underestimates Ambulatory Blood Pressure in an Untreated Employer-Based US Population: Results From the Masked Hypertension Study

Background: Ambulatory blood pressure (ABP) is consistently superior to clinic blood pressure (CBP) as a predictor of cardiovascular morbidity and mortality risk. A common perception is that ABP is usually lower than CBP. The relationship of the CBP minus ABP difference to age has not been examined in the United States. Methods: Between 2005 and 2012, 888 healthy, employed, middle-aged (mean±SD age, 45±10.4 years) individuals (59% female, 7.4% black, 12% Hispanic) with screening BP <160/105 mm Hg and not taking antihypertensive medication completed 3 separate clinic BP assessments and a 24-hour ABP recording for the Masked Hypertension Study. The distributions of CBP, mean awake ABP (aABP), and the CBP−aABP difference in the full sample and by demographic characteristics were compared. Locally weighted scatterplot smoothing was used to model the relationship of the BP measures to age and body mass index. The prevalence of discrepancies in ABP- versus CBP-defined hypertension status—white-coat hypertension and masked hypertension—were also examined. Results: Average systolic/diastolic aABP (123.0/77.4±10.3/7.4 mm Hg) was significantly higher than the average of 9 CBP readings over 3 visits (116.0/75.4±11.6/7.7 mm Hg). aABP exceeded CBP by >10 mm Hg much more frequently than CBP exceeded aABP. The difference (aABP>CBP) was most pronounced in young adults and those with normal body mass index. The systolic difference progressively diminished, but did not disappear, at older ages and higher body mass indexes. The diastolic difference vanished around age 65 and reversed (CBP>aABP) for body mass index >32.5 kg/m2. Whereas 5.3% of participants were hypertensive by CBP, 19.2% were hypertensive by aABP; 15.7% of those with nonelevated CBP had masked hypertension. Conclusions: Contrary to a widely held belief, based primarily on cohort studies of patients with elevated CBP, ABP is not usually lower than CBP, at least not among healthy, employed individuals. Furthermore, a substantial proportion of otherwise healthy individuals with nonelevated CBP have masked hypertension. Demonstrated CBP−aABP gradients, if confirmed in representative samples (eg, NHANES [National Health and Nutrition Examination Survey]), could provide guidance for primary care physicians as to when, for a given CBP, 24-hour ABP would be useful to identify or rule out masked hypertension

Optimization of a parallel permutation testing function for the SPRINT R package

The statistical language R and its Bioconductor package are favoured by many biostatisticians for processing microarray data. The amount of data produced by some analyses has reached the limits of many common bioinformatics computing infrastructures. High Performance Computing systems offer a solution to this issue. The Simple Parallel R Interface (SPRINT) is a package that provides biostatisticians with easy access to High Performance Computing systems and allows the addition of parallelized functions to R. Previous work has established that the SPRINT implementation of an R permutation testing function has close to optimal scaling on up to 512 processors on a supercomputer. Access to supercomputers, however, is not always possible, and so the work presented here compares the performance of the SPRINT implementation on a supercomputer with benchmarks on a range of platforms including cloud resources and a common desktop machine with multiprocessing capabilities

Components of particulate matter air-pollution and brain tumors

Background Air pollution is an established carcinogen. Evidence for an association with brain tumors is, however, inconclusive. We investigated if individual particulate matter constituents were associated with brain tumor risk. Methods From comprehensive national registers, we identified all (n = 12 928) brain tumor cases, diagnosed in Denmark in the period 1989–2014, and selected 22 961 controls, matched on age, sex and year of birth. We established address histories and estimated 10-year mean residential outdoor concentrations of particulate matter ˂ 2.5 µm, primarily emitted black carbon (BC) and organic carbon (OC), and combined carbon (OC/BC), as well as secondary inorganic and organic PM air pollutants from a detailed dispersion model. We used conditional logistic regression to calculate odds ratios (OR) per inter quartile range (IQR) exposure. We adjusted for income, marital and employment status as well as area-level socio-demographic characteristics. Results Total tumors of the brain were associated with OC/BC (OR: 1.053, 95%CI: 1.005–1.103, per IQR). The data suggested strongest associations for malignant tumors with ORs per IQR for OC/BC, BC and OC of 1.063 (95% CI: 1.007–1.123), 1.036 (95% CI: 1.006–1.067) and 1.030 (95%CI: 0.979–1.085), respectively. The results did not indicate adverse effects of other PM components. Conclusions This large, population based study showed associations between primary emitted carbonaceous particles and risk for malignant brain tumors. As the first of its kind, this study needs replication.</p

British signals intelligence and the 1916 Easter Rising in Ireland

Historians for decades have placed Room 40, the First World War British naval signals intelligence organization, at the centre of narratives about the British anticipation of and response to the Easter Rising in Ireland in 1916. A series of crucial decrypts of telegrams between the German embassy in Washington and Berlin, it has been believed, provided significant advance intelligence about the Rising before it took place. This article upends previous accounts by demonstrating that Room 40 possessed far less advance knowledge about the Rising than has been believed, with most of the supposedly key decrypts not being generated until months after the Rising had taken place